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The FDA stated it intends to restrict GLP-1 active pharmaceutical ingredients used in non-FDA-approved compounded drugs that are mass-marketed as alternatives, and it named Hims & Hers directly

To put that in perspective, a person starting at 220 pounds would lose approximately 53 pounds

Leucine reduces the KM of NAD+ for SIRT1 by 50%, meaning you need less NAD+ to activate SIRT1

Effects of glucagon-like peptide 1 on appetite and body weight: Focus on the CNS

Gonzalez C, Venegas G, Fournier PGJ et al (2025) Polyethylene terephthalate (PET) nanoparticles and the physiological effect on intestinal tissue contraction