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In some cases, ashwagandha may: Increase thyroid hormone levels in hypothyroid individuals Decrease thyroid hormone levels in hyperthyroid individuals Help regulate the hypothalamic-pituitary-thyroid (HPT) axis A study on bipolar patients with elevated TSH levels found that ashwagandha supplementation led to a significant reduction in TSH levels

Nutrients, 11 (9), 2073

S., & DeLany, J

One of the physiological substrates of this transporter is acetylcholine, underlying a key role in the non-neuronal cholinergic system in both physiological and pathological conditions, as testified by the occurrence of a natural mutation of OCTN1 in inflammatory conditions such as Crohns Disease (Pochini et al., 2019)