Semaglutide, which is also available under the brand names Ozempic and Rybelsus, is a GLP-1 receptor agonist that has been shown to help people with type 2 diabetes lose weight, lower glucose levels, and protect against diabetes-related heart complications
According to the NICE Clinical Knowledge Summary (CKS) and the British National Formulary (BNF) , the standard treatment for B12 deficiency without neurological symptoms involves: Hydroxocobalamin 1 mg intramuscularly three times weekly for two weeks Followed by maintenance doses of 1 mg every three months For patients with neurological symptoms (such as paraesthesia, numbness, cognitive changes, or gait disturbances), more intensive treatment is required: Hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement occurs Followed by 1 mg every two months for maintenance Pernicious anaemia , an autoimmune condition where the body cannot produce intrinsic factor, requires lifelong treatment
And in the third case, the patient decided to continue the semaglutide just long enough to achieve a target amount of weight loss
As with fever, inflammation aids the fight against pathogens and should therefore not be inhibited unless it is likely to be damaging or fatal in and of itself (11)
Understanding this change could be a deciding factor in keeping coverage for Medicaid enrollees
