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Signs that levothyroxine dose adjustment may be needed include symptoms of hyperthyroidism (anxiety, palpitations, tremor, heat intolerance) or worsening hypothyroidism (fatigue, cold intolerance, weight gain despite GLP-1 use)

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En el estudio han participado 406 personas con diabetes tipo 2 que fueron asignadas aleatoriamente a dos grupos de tratamiento

Some researchers choose even longer intervals, spending 6 to 8 weeks at each dose level, particularly if they notice heart rate increases above 10 beats per minute from baseline