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The full Wegovy escalation runs through 2.4 mg, and as of March 2026, an FDA-approved higher dose of 7.2 mg is now available (Wegovy HD)

Weeks 4-8: Subtle Shifts and Early Progress By about the four-week mark, you might start seeing some actual weight loss

Ideal for those who dont want to wait on monthly delivery

People on the 2.4 mg dose lost more weight than those on other doses: Two trials (STEP 1 and STEP 3) found an average weight loss of 12% and 13% on the 2.4 mg dose in just over a year (68 weeks)

Induction time of related adverse reactions under different routes of administration By retrieving and summarizing the occurrence timelines of adverse reactions for semaglutide across different administration routes from the FDA Adverse Event Reporting System (FAERS) database, we can generate Figure 3