Injections are often the recommended treatment when: You have been diagnosed with pernicious anemia or another condition that impairs B12 absorption
Last reviewed: July 7, 2026 Last updated: July 7, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
For injectable products, extra attention to strength, route, storage, and supplies helps prevent avoidable order errors
What Are the Benefits of B12 Shots
In naturally aged mouse models (1820 months old), daily oral administration of 5-amino-1mq capsules for 12 consecutive weeks significantly reduced NNMT activity and increased NAD+ levels in various tissues (liver, kidney, adipose tissue), along with markedly elevated expression of SIRT1 and SIRT3 proteins