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Brain Function Glutamate (derived from glutamic acid) is the primary excitatory neurotransmitter in the brain

Endnotes and References The efficacy estimand represents efficacy had all randomized participants remained on study intervention (with possible dose interruptions and/or dose modifications) for 52 weeks without initiating prohibited weight management treatments, and assuming participants who took rescue orforglipron would not have received any additional improvement from their randomized study treatment

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