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The hypothalamus serves as the center of the homeostatic system and includes the arcuate nucleus, ventromedial and lateral hypothalamus, and reward systems (amygdala, hippocampus, and nucleus accumbens [NAc])

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Err-KO Mitigates Hippocampal Microglia Ferroptosis in SABD Model To reveal how Err promotes M2 polarization of microglia, we observed hippocampal microglia under electron microscope and found that the mitochondria of the WT-SABD mice (the mitochondria were smaller, the membrane density increased, and the ridge decreased or disappeared), the mitochondria of Err KO-SABD mice were normal in size, and ridge alignment as well as the outer membrane (Fig