almond butter to the apple at lunch and increase to 4 servings Strawberry-Chocolate Greek Yogurt Bark at evening snack
137 A randomized, placebo-controlled, crossover trial involving 30 subjects with mild sleep complaints found 14 days of treatment with 7.5 mg crocetin, a compound extracted from saffron, increased the intensity of sleep drive as measured with EEG
More recently, another study explored NAM supplementation in a golden retriever muscular dystrophy model, demonstrating increased NAD + levels in skeletal muscles and improved skeletal muscle function 266
What is cagrilintide and how does it differ from semaglutide Cagrilintide: Long-acting amylin analog What cagrilintide is: Synthetic analog of amylin (human hormone) Long-acting formulation (weekly dosing) Developed by Novo Nordisk Currently in Phase 3 clinical trials Not yet FDA approved (as of 2024) Paired with semaglutide as "CagriSema" How amylin works naturally: Co-secreted with insulin from pancreatic beta cells Released after meals Slows gastric emptying (food stays in stomach longer) Reduces glucagon secretion Signals satiety to brain Regulates postprandial glucose Cagrilintide's mechanisms: Mimics natural amylin but lasts much longer Dramatically slows gastric emptying Increases satiety and fullness Reduces food intake Lowers postprandial glucose Works on amylin receptors (different from GLP-1) Primary benefits: Powerful appetite suppression Extended feeling of fullness Reduced meal frequency Lower caloric intake Glucose regulation Complements GLP-1 action Learn about peptides , how peptides work , and what are peptides used for in our foundational guides
The trial showed no decrease in sugar crashes but did lead to an average weight loss of 10 pounds
