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& Rodriguez-Palacios, A

GLP-1 receptor agonists work by: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps regulate blood sugar levels Slowing gastric emptying , meaning food remains in the stomach longer, promoting feelings of fullness Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger signals and food cravings Decreasing glucagon secretion , which helps prevent excessive glucose production by the liver Most GLP-1 agonists are administered via subcutaneous injection, typically once weekly or once daily depending on the specific formulation, though oral semaglutide (Rybelsus) is also available

Fatigue was not identified as a frequent side effect in clinical trials, occurring in less than 5% of participants

Rapid weight drop without a proportional change in body composition

L-glutathione works from within by inhibiting the tyrosinase activity to reduce pigmentation and dark spots in the sun-exposed area