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found that signal transducers and activators of transcription 3 (STAT3) promote MYC expression in tumor cells in AML, which in turn regulates the transcription of amino acid transporter SLC1A5, promotes Gln metabolism in AML cells, and oxidative phosphorylation (OXPHOS) of leukemia stem cells (LSCs)

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The case for boosting glutathione and related enzymes Glutathione assumes many roles, and its depletion is observed in aging and many chronic diseases [4-6]

Human exploratory studies remain limited

Park and colleagues (14) demonstrated that zinc-mediated neuronal death following ischemia may be achieved through the specific induction of p75 NTR and its associated death executor, NADE