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Search strategy Two reviewers (LM, DF) systematically searched MEDLINE, Embase, and the Cochrane Library from inception to August 2023 using a comprehensive search strategy combining study design-, intervention-, and diagnosis-related search terms (see Table 1 for a complete list of antioxidants included in the review)

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Induction of Type 1 Diabetes T1DM was induced by a single intraperitoneal injection of 135 mg alloxan (kg body mass) 1 dissolved in 0.2 mL sterile saline 22