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Homocysteine modification in protein structure/function and human disease

Plasma levels of total protein (TP), albumin (ALB), aspartate aminotransferase (AST), alanine aminotransferase (ALT), cholesterol (CHOL), triglycerides (TRIGL), high-density lipoproteins (HDL), low-density lipoprotein (LDL), uric acid (UA), creatinine (CREJ) and glucose (GLU) were measured using automated analyser (Cobas c111 Analyzer, Roche Diagnostics)

Drug solutions, typically 5 mg/ml in HPLC-grade water (except for Dihexa, prepared in DMSO), were added to rat serum, and the mixture was incubated at 37C

These results suggest that there is a pathway downstream of Cyss uptake, but independent of GSH synthesis, that can support OS resistance

doi: 10.1080/09513590.2019.1648413 81 DolmansMMDonnezJ