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5-Oxoprolinase deficiency is a very rare autosomal recessive disease characterized by 5-oxoprolinuria, and a very heterogeneous clinical presentation, including renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly (Njalsson and Norgren, 2005

2.2 Use of Inhaled Glutathione for Treatment Lung infections, including cystic fibrosis, idiopathic pulmonary fibrosis, and lung disease in individuals with HIV