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1d) and were rare in albino FVB-HGF mice 9

However, in the case of products prepared from human plasma, the risk of transmission of pathogens is reduced by epidemiological surveillance of the donor population and selection of individual donors by medical interview

Interim data from an open-label, Phase 1/2 trial reported weekly IV infusions of tividenofusp alfa significantly reduced cerebrospinal fluid (CSF) heparan sulfate (HS) by 91% and urinary HS by 88%key biomarkers of Hunter syndrome that could support an Accelerated Approval. A significant reduction in HS levels was seen at week 24 and maintained through week 201