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If the molecule is broken down into its component amino acids, you aren't really taking glutathione anymore

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After taking a closer look at the lowestenergy conformers of the four abovementioned compounds, it turned out that most of them have the indole ring of the tryptophan aligned along the phenyl ring of the phenylalanine, which indicates a interaction (sample geometries can be found in the Supplementary Information, Figure S2)

doi: 10.1161/hypertensionaha.120.16647 44 TopchiyTArdatskayaMDButorovaLIslovskiiLVinushkinN

This means the medications arent acting on just one pathway, but on many of them at once