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Other symptoms may include: Constipation Sores or swelling in the eyes Draining of pus, mucus, or stools from around the rectum or anus (caused by something called a fistula) Joint pain and swelling Mouth ulcers Rectal bleeding and bloody stools Swollen gums Tender, red bumps (nodules) under the skin, which may turn into skin ulcers Exams and Tests A physical exam may show a mass or tenderness in the abdomen, skin rash, swollen joints, or mouth ulcers

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Neurological symptoms such as paraesthesia, balance problems, or cognitive difficulties typically take 36 months to improve and may continue improving for up to 1218 months