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Short-Term Effects (Days to Weeks): Improved energy levels: Typically within 48 to 72 hours, patients may notice increased energy and reduced fatigue

High-dose vitamin B12 supplements taken concurrently with the injection may lead to excessive B12 levels, though toxicity from vitamin B12 excess is extremely rare due to its water-soluble nature and efficient renal excretion

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Intrinsic factor is a glycoprotein produced in the stomach

A pilot metabolic study demonstrated that a 750 mg NAD+ IV infusion over 6 hours was welltolerated in humans, with rapid metabolic clearance and no acute toxicity [10]