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Understanding Leucovorin and Folate Pathways in Autism Folate (vitamin B9) is crucial for brain development and function, supporting DNA synthesis, methylation, and neurotransmitter production [2]

To evaluate the anticonvulsant test, twenty-three hours after the induction of status epilepticus with intraperitoneal injection of pilocarpine, animals received once again the different treatments (with distilled water for the normal group (lot 1) and the negative control group (lot 2), the plant extract (lots 3 to 6) for the test groups, sodium valproate (lot 7) and piracetam (lot 8), respectively)

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Such observations suggest that perturbations in the microbiotagutbrain axis (MGBA) may play a role in disease initiation or progression