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Nonetheless, the deletion of Nrf2 prevented the increased expression of NRF2 protein and the induction of NRF2 targets upon Gclc deletion in liver tissue (Fig

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Adenosine triphosphate (ATP) levels reduce in the ischemic brain tissue, and ionic transporters Na + -K + -ATPase and Ca 2+ -ATPase lack the substrate for its normal functioning

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5,22 Treatment Evidence-based recommendations for the treatment of lumbar spinal stenosis are complicated by heterogeneity of the condition, a waxing and waning nature, and lack of high-quality studies evaluating its treatment exclusively (many of the studies of lumbar spinal stenosis overlap with other etiologies of chronic low back pain)