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Extra provider scrutiny is warranted for patients with hepatic impairment (Child-Pugh B or C), significant renal impairment (eGFR below 30), high-dose zinc supplementation (above 50 mg/day), active infection at the intended injection site, or age under 18

To prevent this, reorder 710 days before your current vial expires and consider maintaining a one-vial buffer stock if your protocol requires uninterrupted dosing

Zach Mentz is Trending Sports and News Reporter for cleveland.com / The Plain Dealer