Many patients find their cravings for sweet, fatty foods naturally diminish on Wegovy, whilst some experience gastrointestinal side effectssuch as nausea or bloatingthat may worsen with high-fat foods
Semaglutide for weight loss Medically reviewed by Dr Kathryn Basford Last reviewed: 19 Jun 2026 Semaglutide is a type of medication called a glucagon-like peptide-1 (GLP-1) receptor agonist
On the last day of oral contraceptive and semaglutide coadministration, 4 subjects had elevations in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) concentrations that were reported as AEs, including 3 subjects with ALT 3x the upper limit of normal (ULN
The result is a rollercoaster where the first half of the week feels awful and the second half feels like the medication is barely working
While these medications are beneficial for many patients, they are not for everyone, and serious side effects are possible, especially in those with a history of pancreatitis, gallbladder issues, or thyroid tumors