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A person at 0.25 mg and a person at 2.4 mg are having very different experiences of the same drug

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Lean male C57BL/6 mice (8-16 weeks of age, body weight 25-30 g, purchased from Charles River) were maintained at 21-23C and light-dark cycles (12:12 hour schedule, lights on at 07:00)

PlexusDx recommends using a backup contraceptive method (condoms, IUD, or patch) for your first 36 months on therapy and monitoring for breakthrough bleeding