People taking Ozempic have experienced unexpected vision loss, which can occur suddenly due to a stroke behind one or both eyes
Established causes of gastroparesis include diabetes mellitus (diabetic autonomic neuropathy affecting the vagus nerve), post-surgical complications (particularly following gastric or oesophageal surgery), neurological disorders such as Parkinson's disease, connective tissue diseases like scleroderma, and certain medications (including opioids, anticholinergics, tricyclic antidepressants, and GLP-1 receptor agonists)
While the employed rodent model replicates key metabolic and histopathological features of the human condition, and the conservation of the identified target pathways between species supports the biological plausibility of our findings, several critical aspects remain to be fully addressed
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B Vitamins in the nervous system: Current knowledge of the biochemical modes of action and synergies of thiamine, pyridoxine, and cobalamin