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Combined with conjugated estrogens into one drug, bazedoxifene appears to reduce negative effects of estrogen on the endometrium and breast tissue while promoting vulvovaginal and bone health and relieving hot flashes and menopausal symptoms in general 222,248
The most common mutation is a deletion that encompasses the first 10 exons of the gene along with portions of the CARKL gene upstream of CTNS
doi: 10.1021/pr901188e 149 MingXSteinTPBarnesVRhodesNGuoL
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