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However, a breakthrough came with the observation that TICs, rather than the bulk of differentiated tumor cells, thrive in 3D gels [23, 24], offering an opportunity to uncover signaling pathways specific to TIC growth and identify TIC-specific therapeutic targets

Isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis

One safety note: both peptides degrade rapidly and require refrigerated storage

Bowel Obstruction Like intestinal obstructions, a blockage of the large intestine or colon can lead to major health emergencies

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