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Through HDAC6 inhibition, the pathway promotes the removal of damaged cellular components, reducing oxidative stress and enhancing cellular repair mechanisms in retinal cells ( 2.2.3 Beyond the eye In renal tubular cells (Wang et al., 2021) and brain tissue in animal stroke model ( + -dependent deacetylase SIRT1, reducing mitochondrial dysfunction and oxidative stress by decreasing ROS production, thereby preventing apoptosis induced by lipotoxicity

Isoliquiritigenin and licochalcone ASMEDDS further validate this approach, demonstrating XOD suppression, lymphatic transport enhancement, and mitigation of hyperuricemia-induced organ damage (Zhang Y

Most patients received semaglutide via subcutaneous injection for weight loss or blood sugar reduction