Pegloticase: indicated for refractory gout, catalyzes the oxidation of uric acid to highly soluble allantoin, rapidly lowering SUA
While most patients tolerate the treatment well, mild side effects such as headaches or minor discomfort can occasionally occur
Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis
Zooming back out, the table below illustrates the possible impact of the GLP-1 movement on different actors across the food supply chain, highlighting the challenges and opportunities it creates for them

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