Preliminary studies suggest neuroprotective, immunoregulatory, and vision-preserving effects Khavinson et al., Neuroendocrinol Lett , 2003
Biomedicines 11:11
People with obesity or type 2 diabetes often show reduced GLP-1 secretion in response to the same meals that trigger robust hormone release in lean individuals
Jacobs BM, Belete D, Bestwick J, Blauwendraat C, Bandres-Ciga S, Heilbron K, et al
Key findings: Compared to matched controls: 12.8 higher odds of transfusion preterm birth (aOR ~1.8) No significant increase in reported PPH (recent cohort) Important nuance The lack of PPH signal doesnt mean no bleeding risk: Transfusion rates remain high Suggests bleeding + anemia (e.g., iron deficiency) may be underappreciated drivers What this tells us, even in modern care: VWD still impacts maternal outcomes Traditional endpoints (like PPH) may miss part of the picture Pre-delivery optimization (iron, hemostasis) matters as much as delivery management Clinical direction - Multidisciplinary care (Heme + MFM) - Routine iron deficiency screening - Better peripartum planning Ming Y Lim | G Bryce Christensen | George M