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Common adverse effects include: Nausea (reported by 30-40% of patients at the 2.4 mg dose) Vomiting Diarrhea Constipation Abdominal pain Decreased appetite These gastrointestinal symptoms are typically most pronounced during dose escalation and often improve with continued treatment

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The ideal candidate is a patient who has hit a hard plateau on a GLP-1 receptor agonist and complains of significant fatigue or lethargy

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