2023 May Bruce HR Wolffenbuttel, Hanneke JCM Wouters, M Rebecca Heiner-Fokkema, Melanie M van der Klauw
INDICATIONS AND USAGE INDICATIONS & USAGE SECTION Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions ), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
Lagadic-Gossmann D, Lerche C, Rissel M, Joannard F, Galisteo M, Guillouzo A, et al
The reason for this variation is still unknown but may be associated with mutations in the tumor suppressor gene TP53
Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on January 20th, 2024