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Or they may find themselves B12 deficient for other reasons

The oral delivery format may have different bioavailability compared to injectable protocols, and dosing equivalency between administration routes is not definitively established through comparative pharmacokinetic studies

10: Sikiric P, Seiwerth S, Skrtic A, Staresinic M, Strbe S, Vuksic A, Sikiric S, Bekic D, Soldo D, Grizelj B, Novosel L, Beketic Oreskovic L, Oreskovic I, Stupnisek M, Boban Blagaic A, Dobric I

This happens because certain MTHFR mutations (C667T and A129C) lower the amount of active folate being produced in the body, and the use of vitamin B12 requires the active form of folate

This injection is commonly used to treat Vitamin B12 deficiencies and improve overall well-being