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Targeted inhibition of -oxidation with etomoxir, simulating the effect of autophagy blockade, resulted in reduced expression of the fibrogenic genes -Sma, collagen 11, collagen 12, Pdgfr- , and Mmp-2 (218)

discussion 260-268

Treatment decisions are based on individual clinical assessment

The overlapping pathways of our high ADA metabolomic dataset with the studies by Li et al., and Zhou et al., are phenylalanine, tyrosine and tryptophan biosynthesis, phenylalanine metabolism, tyrosine metabolism, arginine biosynthesis, butanoate metabolism and arginine and proline metabolism

According to the International Diabetes Federation (IDF), 589 million adults (20-79 years) are living with diabetes, and in 2024, statistics show that diabetes alone caused 3.4 million deaths