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At $300-450 per month, you are paying a premium for unproven efficacy

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (e.g., different shape or color), as trademark laws prevent a generic from looking exactly like the brand-name drug

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Your dose may increase over time based on your response, but your monthly price stays the same

If you are crossing multiple time zones, the general recommendation is to gradually shift your bupropion timing by one to two hours per day rather than abruptly changing