Transplantation of mSOD1 G93A microglia into PU.1 / mice, which lack macrophages, neutrophils, T- and B-lymphocytes, and microglia, did not induce motor neuron degeneration, confirming that mSOD1 in microglia alone is not sufficient to initiate disease ([17, 18, 35]
Conflict of interest JB is the co-founder of InterRayBio, LLC
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L.PiX.et al (2021)