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The transmembrane receptor TREM2, acting through its adaptor protein DAP12, is also essential for promoting macrophage fusion and multinucleation, particularly in lipid-rich environments such as obesity-associated adipose tissue, where TREM2 functions as a marker of lipid-associated macrophages (157)

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B-12 (cobalamin): Cobalamin or cyanocobalamin is usually just called vitamin B12 when sold as a supplement or listed as an ingredient

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aurantium have been linked to serious clinical adverse events, mostly related to CV issues, including syncope, QT interval prolongation, MI, ischemic stroke, angina, tachycardia, bradycardia, hypotension, vasospasm, ventricular fibrillation, and ischemic colitis (239, 242)