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to capitalize on the diversity of its actions, many stabilized analogs and agonists have been synthesized over the years, extending the half life of somatostatin for sustained treatment effects ( The wide array of effects of somatostatin is mediated by five somatostatin receptor (SST) subtypes (SST1-5), each encoded by a different gene ( i/o resulting in inhibition of adenylate cyclase and a decrease in cAMP levels
& Hoopes, P.C
Am J Physiol 1986;251(4 Pt 1): C496504
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