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Hitz Lindenmuller I, Itin PH, Fistarol SK
For melasma, it is critical to use only a non-heating LED device as heat is one of the most significant melasma triggers and thermal devices can cause significant worsening
As patient access improves and awareness spreads, the demand for these therapies will increase, despite challenges like high treatment costs and market competition. - Shambhu Nath Jha, Principal Consultant at Fact MR
It has been reported that IGFBP-3 binds to a nuclear receptor, 9-cis retinoic acid receptor-alpha (RXR-), which interacts with peroxisome proliferator activated receptor-gamma (PPAR-), a nuclear protein involved in the regulation of glucose and lipid metabolism [175, 176]