Altern Med Rev 1997;1:155-176 View Full Paper [4] Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C
In bronchial epithelial cells, renal epithelial cells, and neurons, ALOX15 binds to phosphatidylethanolamine-binding protein 1 (PEBP1) and triggers RSL3-induced ferroptosis (65)
Moreover, researchers fused TALEN to the Pseudomonas aeruginosa type III secretion system effector ExoS54 signal peptide and a nuclear localization signal, enabling direct cytosolic delivery and subsequent nuclear translocation of functional TALEN protein into human HeLa cells via bacterial injection, achieving targeted knockout of the Venus reporter gene [114]
Note: AMS, acute mountain sickness
Together, glutathione and NAD+ can complement one another by supporting cellular repair, energy production, and detoxification