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Meanwhile, changes in quality-of-life scores measured by the Short Form-36 (SF-36) physical and mental components were small and not clinically significant across groups [1]

it is more about the bodys adaptation to the drug

Growth hormone promotes lipolysis (fat breakdown) and shifts metabolism toward preferential use of fat for energy

For example, it has been demonstrated that compared with adjacent normal tissues, the monounsaturated fatty acids (MUFAs) level in TC tissues is significantly elevated in TC [103], along with that, the serum level of MUFAs is decreased [104]