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A standard clinical dose starts at 2mg once weekly, escalating to 4mg, 8mg, and 12mg every 4 weeks per Phase 2 data

Mitochondrial function was severely compromised on multiple levels, including abnormalities in mitochondrial biogenesis (PGC1), nutrient sensors regulating fatty-acid entry into mitochondria (pAMPK/AMPK, SirT3, CPT1b), mitochondrial -oxidation of fatty-acids (HADHA, PPAR), electron transport chain complexes (I, II, III, V), ATP synthesis (ATP5A), and mitophagy (PINK1)

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In search of solutions to this problem, young people who are seeing these factors at an earlier age, who would have normally sought us out 10 or 15 years later, do seek treatment from us, says Dr

NAC crosses the blood-brain barrier, increases brain GSH levels, and acts as a glutamine modulator (11)