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We are the first meta-analysis comparing the different administration routes of vitamin B12, and the first meta-analysis includes the SL route of administration in the analysis

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In a single-dose trial, semaglutide exposure was highest when administered with 300 mg of SNAC, compared with 150 mg or 600 mg [65]

A wide range of non-motor manifestations, including hyposmia or anosmia, gastrointestinal disturbances like chronic constipation, rapid eye movement (REM) sleep behavior disorder, autonomic dysfunction, mood changes like depression and anxiety, and progressive cognitive impairment, account for a significant portion of the disease burden [3]