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According to the longest available trial on the compound, the most commonly experienced side effects include [16]: Increase in appetite (67%) Joint pain (58%) Mild lower extremity edema (44%) Mild muscle pain (33%) The researchers reported that all of these complaints subsided within a few months of discontinuing MK-677 therapy [16]

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Abstract The present study aimed to investigate the protective effects of platelet-rich plasma combined with post-conditioning on testicular ischemiareperfusion injury in a rat model

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