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Nevertheless, although off-target inhibition of DPP-9 could be one potential explanation for the association between saxagliptin and heart failure in an experimental setting, it is uncertain whether mean exposure levels of saxagliptin reach a high enough level to affect DPP-9 activity when used at its therapeutic dose in humans

High-pressure microscopy for tracking dynamic properties of molecular machines

PloS One (2012) 7:e51593

Almost every time I pushed through, I regretted it

BED, bulimia nervosa (BN) and anorexia binge-purge type have also been found to be associated with a condition known as Loss of Control Binge Eating (LCBE), which has a complex etiology (47)