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doi: 10.3389/fimmu.2018.00402

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Thus, in overweight/obese women with PCOS, combination treatment is more effective than metformin alone by improving insulin sensitivity, with tolerable short-term side effects (201)

Here's what matters: the compounds inside Lipo C (methionine, inositol, choline, and often B12) have genuine metabolic roles in fat oxidation and liver function, but their effectiveness depends entirely on whether the patient has an underlying deficiency or metabolic bottleneck that supplementation can address