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The mechanism by which food-derived flavonoid compounds induce ferroptosis to inhibit tumors is detailed in Figure 5B

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Additionally, the coordinated control of glycolysis and gluconeogenesis in the liver is adjusted by the phosphorylation state of the enzymes that catalyze the formation of a potent activator of glycolysis called fructose 2,6-bisphosphate

GLP-1s directly mimic a hormone that regulates appetite and insulin, while berberine works through multiple pathways, including AMPKL activation and by tweaking the gut microbiome

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