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Pharm Res 36:99 Jain AB, et al (2024) Use of once-daily oral semaglutide and associated clinical outcomes among adults with type 2 diabetes in routine clinical practice in Canada: a multicentre, prospective real-world study (PIONEER REAL Canada)

Here we show that GLP-1 RAs are associated with lower risks of mortality, major cardiovascular events (MACEs), and major adverse kidney events (MAKEs) in type 2 diabetes patients with acute kidney disease (AKD)

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There is no standardized concentration because these are compounded products, not FDA-approved drugs with fixed formulations

Compared with normal tissues and their Ti-EVs, CA9, CD70, and CD147 were increased in tumor tissues and their Ti-EVs