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Buse JB, Garber A, Rosenstock J, Schmidt WE, Brett JH, Videbaek N, et al
May 13th, 2025: Emerging Health Concerns Linked to Ozempic and Related GLP-1 Medications As the use of GLP-1 drugs like Ozempic, Wegovy, and Zepbound continues to rise, doctors are reporting a concerning side effect: Ozempic feet. This term describes the discomfort and pain some users experience as a result of rapid weight loss, which reduces the natural fat padding on the soles of the feet
It works to improve insulin sensitivity and help with excess weight
In clinical trials, dyspepsia (which can include reflux-like symptoms) was reported in the prescribing information for semaglutide products, though specific rates of reflux or GERD are not consistently quantified across all formulations