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Closer attention to technical aspects in trial design is driving successes in clinical trials in systemic lupus erythematosus and stimulating much additional interest in the rational design and application of novel LN therapies

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Researchers adjust glutathione levels or measure its oxidized and reduced forms (GSH/GSSG) to probe oxidative stress and cellular responses

identified a positive correlation between DPP-IV activity in the islet and insulin secretion (115), suggesting that islets can intrinsically regulate DPP-IV to promote islet function

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