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Pathophysiological role of BACH transcription factors in digestive system diseases

32 Tirzepatide, a GLP-1R-GIPR co-agonist, exhibits superior insulin responses and potent glucose-lowering and weight-loss effects compared to existing GLP-1R agonists

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Murray 1993

The final product, liraglutide (Victoza, Novo Nordisk), proved its effects in type 2 diabetes mellitus (T2DM) and was approved by the FDA in 2010 [19]